Behavioral Research Blog

How to let rats run perfectly

Posted by G. Smit on Aug 14, 2015

In a recent blog post, we talked about letting animals walk freely in gait research. 

At Noldus, we strongly believe that this is the way to go in gait research, so our CatWalk XT system makes use of free gait. This is consistent with the constant feedback from, and collaborations with, scientists who actually perform gait, locomotor, or pain research.

Read More

Topics: rats, CatWalk XT, gait analysis, locomotion

Behavioral effects of optogenetically induced myelination in mice

Posted by G. Smit on Jul 16, 2015

Myelination, the ‘ensheathment’ of neurons, is essential to the functioning of the central and peripheral nervous systems. So it is not surprising that problems with myelination can lead to a number of crippling diseases. Known examples include multiple sclerosis and other neurodegenerative autoimmune diseases.

Read More

Topics: mice, CatWalk XT, gait analysis, locomotion

How to study ataxia

Posted by G. Smit on Jul 3, 2015

Gait and motor performance are studied extensively in neuroscience research, which is not surprising when you come to think of it, because it is affected in many neurological diseases. Ataxia is a common problem in Parkinson’s disease (PD), and many early onset Alzheimer’s disease patients (AD) also deal with it. Motor skills are also affected in patients with autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD).

Read More

Topics: Alzheimer's disease, Parkinson's Disease, gait analysis, ErasmusLadder, motor learning, reflexive motor learning, motor performance, cerebellum, motor control

Gait research: let your animals walk freely

Posted by G. Smit on Apr 15, 2015

Researchers use different ways to analyze gait in animals. Basically we can distinguish two methods: one can either observe or measure gait in an unrestricted manner, or one chooses a forced manner, such as a treadmill or treadwheel.

Read More

Topics: Parkinson's Disease, CatWalk XT, gait analysis, spinal cord injury, ataxia, locomotion

10 Innovative behavioral studies on Alzheimer’s and Parkinson’s

Posted by G. Smit on Mar 17, 2015

Tomorrow the 12th International Conference on Alzheimer’s and Parkinson’s diseases (ADPD) in Nice, France starts. Last week I blogged about a study on Ginkgo biloba and Alzheimer's, and I thought this would be a great opportunity to highlight some more studies and get you in the mood for the conference. This blog post features 10 interesting studies that use innovative techniques to study models of AD and PD and important underlying neuronal mechanisms.

Read More

Topics: EthoVision XT, mice, Alzheimer's disease, Video tracking, zebrafish, Danio rerio, DanioVision, Parkinson's Disease, learning and memory, rats, CatWalk XT, gait analysis, locomotion, top 10, ErasmusLadder, reflexive motor learning, motor performance

Parkinson’s & gait impairment: comparing rats and humans

Posted by G. Smit on Feb 5, 2015

When you hear about Parkinson’s disease (PD), the first thing that comes to mind is probably impaired movement. And that there is no cure. As PD is one of the most common neurodegenerative diseases, you can imagine why it is the focus of many drug development and clinical studies.

Read More

Topics: Parkinson's Disease, rats, CatWalk XT, gait analysis, locomotion

5 Days of Neuroscience 2014

Posted by Annelies Verkerk on Nov 4, 2014

The 2014 Neuroscience conference is fast approaching, and will be held on November 15-19 in Washington, DC! This year promises another inspiring program. We’ve highlighted some activities for you to get into the Neuroscience mood!

Read More

Topics: Video tracking, gait analysis, neuroscience, conferences, SfN

Most and least popular posts of 2013 (animal behavior research)

Posted by G. Smit on Dec 31, 2013

It seems inevitable: the end-of-year lists. And yes, here at the Noldus blog, you can find them too. I did not want leave 2013 behind us without mentioning our three most popular blog posts on animal behavior research of this year. While 13 might not be a lucky number for some, we have had a great year in which we saw a lot of growth in zebrafish research and the combination of optogenetics and behavior. Not surprisingly, these two topics showed up in our top 3.

Read More

Topics: EthoVision XT, mice, Video tracking, The Observer XT, animal behavior research, video observation, fish, zebrafish, Danio rerio, DanioVision, Parkinson's Disease, rats, birds, CatWalk XT, gait analysis, arthritis, monkey, locomotion, 2013

Using CatWalk gait analysis to study monoarthritis in mice

Posted by G. Smit on Sep 19, 2013

Researchers are always looking for new ways to alleviate symptoms of arthritis. The CatWalk XT has been shown to be very useful in research involving arthritis in rodent models. Most of the research done on arthritis with CatWalk has been done with rats, but Parvathy et al. decided that they would use mice in their experiment, being that mice are frequently used in disease studies and they are the preferred animal for genetic modifications when studying biology and disease. The researchers looked at both static and dynamic parameters in this experiment.

Read More

Topics: mice, CatWalk XT, gait analysis, arthritis

CatWalk gait analysis versus treadmills

Posted by G. Smit on May 13, 2013

Traditionally, there are two fundamentally different ways to analyze gait in animals. One can either observe or measure gait in an unrestricted manner, or in a forced manner, as seen when using a treadmill or treadwheel.

Read More

Topics: rats, CatWalk XT, gait analysis, foot prints

Subscribe to Email Updates

Posts by Topic

see all