Behavioral Research Blog

How to measure the social behavior of Fragile X mice

Posted by G. Smit on Feb 20, 2015

Fragile X syndrome (FXS), formerly known as mental retardation, is a common developmental disorder with a prevalence of 1 in 3600 to 4000 males and 1 in 4000 to 6000 females (www.fragilex.org). Besides the intellectual challenges, patients often show behavioral abnormalities, which in a large part of the male patients strongly resembles autism-like behavior. Unfortunately, treatment of FXS is limited to the symptoms – think of behavioral therapy or pharmaceuticals to treat attentional deficits, anxiety, and impulse control problems.

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Topics: mice, social hierarchy, automated tube test, Fragile X syndrome

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